Commentary: Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

Aiming for Study Comparability in Parkinson’s Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

Prodromal Markers in Parkinson’s Disease: Limitations in Longitudinal Studies and Lessons Learned

A growing body of evidence supports a prodromal neurodegenerative process preceding the clinical onset of Parkinson's disease (PD). Studies have identified several different prodromal markers that may have the potential to predict the conversion from healthy to clinical PD but use considerably different approaches. We systematically reviewed 35 longitudinal studies reporting prodromal PD featur...

کاربرد سلول های بنیادی در درمان بیماری پارکینسون

Stem cells are undifferentiated cells with the ability to divide and differentiate into distinct cell types. The source of these cells is from embryos and adults, that each cell has its own specific characteristics. For nearly decades, experimental studies have been conducted to use these types of cells to treat various diseases. Parkinson's disease is one of the most common neurodegenerative d...

The Principles and presupposions in the approach for for commentary according to the descending order of Quran

Qurnic commentary based on the order of descending is regarded as one of the modern methods in Quranic commentary. Some assessments, however, have been presented on the validity and authenticity and consequences of the method. The main part of the assessments has centered on possibility or impossibility of agreeable principles and presupposions for the method. The presupposions of the method ha...

مدل‌سازی توام داده‌های بقا و طولی و کاربرد آن در بررسی عوامل موثر بر آسیب حاد کلیوی

Background: In many clinical trials and medical studies, the survival and longitudinal data are collected simultaneously. When these two outcomes are measured from each subject and the survival variable depends on a longitudinal biomarker, using joint modelling of survival and longitudinal outcomes is a proper choice for analyzing the available data. Methods: In this retrospective archiv...